Meloxicam should not be used in patients with which condition?

Meloxicam, a nonsteroidal anti-inflammatory drug (NSAID), should not be used in patients with NSAID hypersensitivity due to the risk of serious allergic reactions. Individuals who have a known hypersensitivity to NSAIDs may experience anaphylaxis, urticaria, or other types of allergic responses when exposed to meloxicam. This reaction can be life-threatening, making it crucial that such patients avoid meloxicam and other NSAIDs altogether.

In contrast, while acute pain, hypertension, and diabetes are relevant medical conditions, they do not outright contraindicate the use of meloxicam. Patients with acute pain often benefit from NSAIDs like meloxicam, and while caution may be warranted in those with hypertension or diabetes due to potential cardiovascular effects, these conditions do not equate to the same level of risk as NSAID hypersensitivity. Therefore, ensuring the safety of a patient with an established allergy to NSAIDs is paramount in clinical practice.